K. Fukushima, Yue Lu, T. Ibata
Nov 15, 1996
Citations
0
Influential Citations
6
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
The Rh2(OAc)4-catalyzed reactions of diazoacetates with diisopropylcyanamide gave 5-alkoxy-2-aminooxazoles. Their isolation was achieved by introduction of a bulky alkoxy group at 5-position. The 5-alkoxy-2-aminooxazole reacted with methanol to give a 1 : 1-adduct in a quantitative yield. The kinetic study indicates that this reaction proceeds in a stepwise mechanism including an equilibrium of the 5-alkoxy-2-aminooxazole with a nitrile ylide intermediate.