Rfc Brown, M. Butcher, R. Fergie
1973
Citations
0
Influential Citations
5
Citations
Journal
Australian Journal of Chemistry
Abstract
Pyrolysis of chloroacetamides RNHCOCH2Cl at 780-850°C/0.1-0.4 mm with short contact time gives nitriles RCN in 45-60% yield (R = phenyl, o- tolyl, p-tolyl, benzyl, or cyclohexyl). A mechanism is proposed involving the formation of the iso-nitrile RNC, formaldehyde, and hydrogen chloride. N-Chloroacetylbiphenyl-2-amine gives biphenyl-2- carbonitrile (45%) and phenanthridine (15%).