Leonhard S. Wolfe, K. Rostworowski, Jean Marion
Jun 7, 1976
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0
Influential Citations
120
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Quality indicators
Journal
Biochemical and biophysical research communications
Abstract
Abstract Thromboxane B2 was formed from endogenous precursors during short incubations of guinea pig and rat cerebral cortex. The amount formed by guinea pig brain tissue was 5–6 times the formation of prostaglandin F2α and E2. Noradrenalin stimulated and indomethacin and mercaptoethanol inhibited thromboxane B2 formation. The mass spectrum of the brain compound was identical to thromboxane B2 formed from arachidonic acid by guinea pig lung and human platelets.