M. D. Roydhouse, J. Walton
Mar 1, 2007
Citations
0
Influential Citations
8
Citations
Journal
European Journal of Organic Chemistry
Abstract
Treatment of 3-[4-(2-bromophenyl)-2-phenylbutyryl]-4,4-dimethyloxazolidin-2-one with LDA in THF launched a domino rearrangement sequence ending in the assembly of a tetracyclic cyclopentaoxazolo[3,2-b]isoquinolin-6-one derivative. Two mechanisms involving an SRN1-type process were proposed. EPR spectroscopic and 13C-labelling experiments suggested that both were operative.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)