H. D. Showalter, J. Domagala, J. P. Sanchez
Dec 1, 1981
Citations
0
Influential Citations
7
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
Starting from readily available 1,2-dihydro-6-methyl-2-oxo-3-pyridinecarbonitrile, 1, viable synthetic pathways to a number of C-6 functionalized 1,2-dihydro-2-oxo-3-pyridinecarbonitriles and corresponding acids are presented. Through the utilization of dianion chemistry, the C-6 methyl substituent is selectively functionalized to three different oxidation levels.