W. Adam*, Chrisostomos Babatsikos, G. Cilento
May 1, 1984
Citations
0
Influential Citations
5
Citations
Journal
Zeitschrift für Naturforschung B
Abstract
Hydroxymethyl-substituted 1,2-dioxetanes (3) have been converted in reasonable yields (10-40%) into the carboxylate-substituted 1,2-dioxetanes (4) by means of the Brewster-Ciotti or Mitsunobu esterification and into the tosylate-substituted 1,2-dioxetanes (5) by means of tosyl chloride in pyridine. The fact that hydroxy-functionalized 1,2-dioxetane can be chemically attached to carboxylic acids and sulfonic acids whit preservation of the dioxetane moiety opens up new opportunities for biomedical applications