H. Bruderlein, M. Kraml, D. Dvornik
1977
Citations
0
Influential Citations
7
Citations
Journal
Clinical biochemistry
Abstract
1. A gas-liquid chromatographic (GC) method for the analysis of butriptyline in serum has been development. Quantitation is based on the peak height ratio between butriptyline and promazine used as internal standard. A triple partition provides a "clean" extract. A detection limit of 10 ng/ml is achieved. 2. The usefulness of the method has been demonstrated in bioavailability studies in dogs.