Kirill A. Khistiaev, M. Novikov, A. Khlebnikov
Feb 11, 2008
Citations
0
Influential Citations
14
Citations
Journal
Tetrahedron Letters
Abstract
Abstract A simple one-step synthesis of a new class of fluorinated heterocycles, 4-fluoro-3-oxazolines, from diarylmethanimines, trifluoroacetophenones and CF 2 Br 2 is described. The reaction proceeds via the sequential formation of difluorocarbene and a gem -difluorosubstituted NH-azomethine ylide, followed by 1,3-dipolar cycloaddition with a ketone.