James A. Bartley, Charles J. Epstein
Apr 29, 1980
Citations
0
Influential Citations
24
Citations
Journal
Biochemical and biophysical research communications
Abstract
Abstract The mean activity of glycinamide ribonucleotide synthetase of fibroblasts from fetuses with trisomy 21 is 1.64 — times that of normal cells. This gene dosage effect is confirmatory of the assignment of the gene for this enzyme to human chromosome 21.