T. McMahon, Jose M. Medina, Yun-Fang Yang
Mar 20, 2015
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0
Influential Citations
44
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Journal
Journal of the American Chemical Society
Abstract
We report the generation of the first 3,4-piperidyne and its use as a building block for the synthesis of annulated piperidines. Experimental and computational studies of this intermediate are disclosed, along with comparisons to the well-known 3,4-pyridyne. The distortion/interaction model is used to explain the observed regioselectivities.