Yuanyuan Tang, D. Reddy, Biao Yu
Dec 1, 2020
Citations
0
Influential Citations
3
Citations
Journal
Tetrahedron
Abstract
Abstract A new dehydrative glycosylation protocol that proceeds through selective activation of glycosyl hemiacetals with nonafluorobutanesulfonyl fluoride (NfF) has been disclosed. Contrary to the major classical glycosylation reactions that proceed under acidic or neutral conditions, the present glycosylation reaction proceeds under mild basic conditions. In the absence of an external acceptor, self-condensation of the glycosyl hemiacetal occurs, providing the corresponding symmetrical 1,1’-disaccharides in high yields.