Rebeca G Balasingham, Catrin F. Williams, H. Mottram
Aug 3, 2012
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Influential Citations
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Organometallics
Abstract
A series of mono- and dimetallic Au(I) triphenylphosphine complexes derived from 1,2-, 1,4-, and 1,8-dialkynyloxyanthraquinone have been prepared. The photophysical and cytotoxic behavior of the ligands and complexes have been explored, with all of the complexes showing both appreciable cytotoxicity against the MCF-7 carcinoma cell line and useful room-temperature anthraquinone-based visible luminescence, which allowed their successful application as fluorophores in cell imaging microscopy. The implications of the photophysical and toxicological properties for the design and investigation of gold-based anticancer agents are discussed.