T. Tomita, Yu-jun Li, T. Nakaya
Jul 28, 1999
Citations
0
Influential Citations
12
Citations
Journal
Chemistry of Materials
Abstract
We reported herein that 2-(methacrylorloxy)ethyl-2-(trimethylammonium)ethyl phosphate (MTP) was successfully grafted onto a segmented polyurethane (SPU) cast film surface. We found MTP orientated onto a film surface had excellent hemocompatibility, and the addition of the cross-linking agent N,N‘-methylenebisacrylamide (MBAA) further increased MTP orientation on the surface and lead to better hemocompatibility. 1,4-Butanediol (BD) as a chain extender was used to synthesize the SPU which was based on diphenylmethane diisocyanate (MDI), vinyl group-containing poly(butadiene) diol (PBD), and hydrogenated poly(butadiene) diol (HPBD). To obtain an alcohol-orientated surface of SPU, glycidyl methacrylate (GMA) was copolymerized with the SPU using α,α‘-azobis(isobutyronitrile) (AIBN) as a radical initiator, and diethanolamine (DEA) was used to open the epoxy group leading to hydroxylated SPU. Furthermore, MTP and the cross-linking agent MBAA were grafted onto the cast film surface of hydroxylated SPU by using di...