Jyotsna, R. S. Dhillon
2009
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Journal
Pesticide Research Journal
Abstract
Dehydrocostus lactone, one of the sesquiterpene lactones of Saussurea lappa was converted to pyrazoline derivative and cyclopropyl and their hydroxyl derivatives to know more about structure activity relationship. Dehydrocostus lactone on hydroboration-oxidation yielded two mono-ols of which the exomethylene conjugated to lactone moiety at C13 remained intact. The structures of these products were ascertained on the basis of IR, 1H NMR and chemical studies. The transformed products were tested for their biological activity. The bioefficacy of dehydrocostus lactone and its transformed products on germination and shoot length of Vigna radiata showed that the chemical modification altered growth regulatory response. The transformed products especially at lower concentrations stimulated shoot growth in mungbean.