S. Lee, M. Rho, Jung-Yeon Nam
Jul 1, 2004
Citations
0
Influential Citations
14
Citations
Quality indicators
Journal
Planta medica
Abstract
Bioactivity-guided fractionations for ACAT inhibitor led to the isolation of guineensine from the CHCl (3) extract of Piper longum. Its structure was identified by spectroscopic means (IR, UV, MS and NMR). Guineensine inhibited ACAT activity in a dose-dependent manner with an IC (50) value of 3.12 micro M.