Mara E. F. Braibante, Günter Clar, M. Martins
Jul 1, 1993
Citations
0
Influential Citations
66
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
1-Methyl-5-(trifluoromethyl)-1H-pyrazoles (2 and 3) and 4,5-dihydro-1-phenyl-5-(trifluoromethyl)-1H-pyrazol-5-ol (4) were prepared by reaction of 4-alkoxy-1,1,1-trifluoro-3-alken-2-ones (1) and hydrazine, methylhydrazine, and phenylhydrazine, respectively, in good yields. Compound 1 proved to be a versatile building block for the regiospecific construction of pyrazole rings having an 5-trifluoromethyl substituent