S. Sukdolak, S. Solujic, N. Manojlovic
Jul 1, 2004
Citations
0
Influential Citations
22
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
3-Acetyl-4-hydroxy-chromen-2-one (1) was brominated with phenyltrimethylammonium tribromide to afford 3-(2-bromoacetyl)-4-hydroxy-chromen-2-one (2) whose reactions with thiourea, thioacetamide and ammonium dithiocarbamate gave respectively 3-(2-amino-thiazol-4-yl)-4-hydroxy-, 4-hydroxy-3-(2-phenyl-thiazol-4-yl)- and 4-hydroxy-3-(2-mercapto-thiazol-4-yl)chromen-2-one. In a similar manner, com pound 2 was treated with four 1-substituted-2-thioureas and thiobenzamide to give the corresponding 4-hydroxy-3-(thiazol-4-yl)-chromen-2-one derivatives.