P. Young, Y. Yosaatmadja, P. Harris
Jan 26, 2017
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0
Influential Citations
12
Citations
Journal
Chemical communications
Abstract
The hydrolysis potential of ester bonds in covalently cross-linking proteins is captured in our novel protein ligation technology. This new type of "molecular superglue" based on the spontaneously-formed Thr-Gln ester bonds found in cell-surface adhesins, affords a unique mechanism to both rationally assemble and disassemble complex protein nanomaterials.