S. Bala, Sunil Kamboj, Ashok Kumar
2010
Citations
1
Influential Citations
26
Citations
Quality indicators
Journal
Journal of Pharmacy Research
Abstract
The chemistry of heterocyclic compounds has been an interesting field of study for a long time. Heterocyclic nucleus 1,3,4-oxadiazole constitutes an important class of compounds for new drug development. The synthesis of novel oxadiazole derivatives and investigation of their chemical and biological behavior have gained more importance in recent decades. Oxadiazole compounds possess an extensive spectrum of pharmacological activities. In particular, compounds bearing 1,3,4-oxadiazole nucleus are known to exhibit unique antiinflammatory, analgesic, antimicrobial, antitumor, anticonvulsant, anthelmintic, antimycobacterial, herbicidal, antioxidant and antiviral activities. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. These observations have been guiding for the development of new oxadiazole derivatives that possess varied biological activities and can be a lead nucleus for future developments to get safer and effective compounds. References of the most relevant literature published by various research groups around the world are provided.