M. Brockwell, A. G. Caldwell, N. Whittaker
1981
Citations
0
Influential Citations
7
Citations
Journal
Journal of The Chemical Society-perkin Transactions 1
Abstract
The enantiomers of the two diastereoisomers of 5-(6-carboxyhexyl)-1-(3-cyclohexyl-3-hydroxypropyl)hydantoin have been synthesised. Potent inhibition of platelet aggregation in this series is associated with the configuration corresponding to that in the natural inhibitors, such as prostaglandins E1 and D2.