Raquel de Oliveira Lopes, Joyce Benzaquem Ribeiro, A. S. Ramos
Oct 15, 2011
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Influential Citations
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Journal
Tetrahedron-asymmetry
Abstract
Abstract Microorganisms were used to reduce 4-bromoacetophenone to ( S )-4-bromophenylethanol and ( R )-4-bromophenylethanol. After a fractional factorial design to identify the important variables for this reaction, Geotrichum candidum provided a 98.9% conversion with >99% ee of the ( R )-isomer, while Rhodotorula rubra led to a 97.6% conversion with a 98.8% ee of the S -isomer.