HiroiKunio, SatoShuko, KitayamaRyuichi
Dec 5, 1980
Citations
0
Influential Citations
11
Citations
Journal
Chemistry Letters
Abstract
The benzoxathiazine 2-oxide derivatives (2a–f) were prepared by reaction of the aminophenols (1a–f) with thionyl chloride in good yields. Equilibrium of 2a (R1=α-C10H7, R2=CH3) with hydrogen chloride and subsequent reaction with phenylmagnesium bromide followed by action of methyl- or butyllithium gave (S)-(−)-4a or (S)-(−)-4b with high enantiomeric excess, respectively.