A. Lee, Hui-Chun Yang, Feng-Yih Su
Jan 8, 2001
Citations
0
Influential Citations
36
Citations
Journal
Tetrahedron Letters
Abstract
Abstract A series of carboxylic acids was transformed to their corresponding methyl esters under CBr 4 /CH 3 OH (0.05 eq., 5 ml) reaction conditions. The rate of esterification is decreased with increasing bulkiness of the alcohol. Chemoselectivity can be achieved between phenylacetic and benzoic acids, sp 3 -C and sp 2 -C acids as well as between sp 3 -C and sp -C tethered carboxylic acids.