Masatomi Kanai, M. Yasumoto, Yokusu Kuriyama
Mar 1, 2003
Citations
0
Influential Citations
33
Citations
Journal
Organic letters
Abstract
[reaction: see text] The highly regioselective hydrogenolysis of bis(alpha-methylbenzyl)amine derivatives proceeded with influence not from the electronic effect but from the steric effect of the trifluoromethyl substituent on the aromatic ring to provide a practical asymmetric synthesis of trifluoromethyl-substituted alpha-phenylethylamines.