Ya Li, T. Zheng, W. Wang
Feb 1, 2012
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0
Influential Citations
23
Citations
Journal
Advanced Synthesis & Catalysis
Abstract
A highly stereoselective and practical synthesis of a-trichloromethyl amines by nucleo- philic trichloromethylation of N-(tert-butylsulfinyl)- A with chloroform was achieved. The obtained a-trichloromethyl amines can be further trans- formed into chiral 2,2-dichloroaziridines through an intramolecular nucleophilic substitution methodolo- gy. 2,2-Dichloroaziridines can also be produced di- rectly from chloroform and N-(tert-butylsulfinyl)- A through a one-pot procedure.