A. Lei, Xiyan Lu
Jul 6, 2000
Citations
0
Influential Citations
36
Citations
Journal
Organic Letters
Abstract
The high regio- and stereoselectivity have been obtained from the allylic substitution reaction catalyzed by palladium(II) species. From allylic alcohols, one-pot reaction with tosyl isocyanate followed by palladium(II)-catalyzed allylic substitution gives N-tosyl (E)-allylic amines in high yield. The substitution occurs only at the γ-position of the 1- or 3-substituted allylic alcohols.