Yining Xuan, Shao-Zhen Nie, Li‐ting Dong
Apr 2, 2009
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Influential Citations
73
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Quality indicators
Journal
Organic letters
Abstract
Highly enantioselective synthesis of nitrocyclopropanes was achieved via the organocatalytic conjugate addition of dimethyl bromomalonate to nitroalkenes and the consequent intramolecular cyclopropanation. 6'-Demethyl quinine was found to be the efficient catalyst. Excellent enantioselectivities, diastereoselectivities, and good yields were obtained for a variety of aryl or heteroaryl nitroethylenes.