M. Journet, D. Cai, J. Kowal
Dec 24, 2001
Citations
0
Influential Citations
48
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Synthesis of variously 5-substituted-4-carbaldehyde-1,2,3-triazole derivatives 2 was accomplished by reacting sodium azide with α,β-acetylenic aldehydes 1 in DMSO at room temperature. Therefore, the reaction remains basic avoiding the generation of the hazardous explosive HN 3 , resulting in a safe process. This mild and general reaction was instantaneous and was essentially quantitative.