M. Friedman, K. Shull, E. Farber
Mar 31, 1969
Citations
1
Influential Citations
48
Citations
Quality indicators
Journal
Biochemical and biophysical research communications
Abstract
Abstract Ethionine ethylates rat liver nuclear proteins in a highly selective manner. The proteins most ethylated are those insoluble in 20–40% (NH 4 ) 2 SO 4 in the saline soluble fraction. With L-ethionine-ethyl-1- 14 C, only one peak of radioactivity was found. This peak has been tentatively identified as an ethyl analogue of methylguanidino arginine, recently reported to occur in nuclear proteins. No radioactive ethionine was found in the proteins after giving ethyl-labeled or 35 S-labeled ethionine. The pattern of labeling with methionine-methyl- 14 C is more complex and is presented.