C. Heim, M. Hartmann
Feb 18, 2022
Citations
0
Influential Citations
5
Citations
Journal
Acta Crystallographica. Section D, Structural Biology
Abstract
Using the MsCI4 soaking system, the binding of the next-generation thalidomide-derived immunomodulatory drugs avadomide (CC-122) and iberdomide (CC-220) to cereblon was characterized at high resolution, highlighting the utility of the MsCI4 system for studies of the structure–activity relationship of cereblon effectors.