M. A. Cowan, P. Mann
Apr 1, 1971
Citations
0
Influential Citations
13
Citations
Journal
British Journal of Dermatology
Abstract
^n-Hexadecane has been used in giiinea-pift skin to produce a transient hyperplasia which has been studied by light and electron microscopy. The changes involved all layers of the epidermis, and most organelle systems. Ultrastructural abnormalities persisted for some time after the skin had returned to normal, as judged by light microscopy. Keratinization was disturbed after 4 applications of hexadecane. but this cannot be attributed to any single mechanism.