A. Warshawsky, Nurit Shoef, A. Tishbee
Dec 1, 1983
Citations
0
Influential Citations
4
Citations
Journal
Journal of Liquid Chromatography & Related Technologies
Abstract
Abstract Bis(2,4-dinitrophenylation) of oligomeric ethylene glycols of the formula HO-(CH2CH2O)n-H (n=4–16)to the corresponding DNP-C(CH2CH2-O) -DNP (where DNP stands for 2,4-dinitrophenyl) provides chromophoric derivatives, which are separated chromatographically on HPLC column. The bis(2,4-dinitrophenyl) glycols are stable in presence of triethylamine, but undergo ethanolysis in presence of hydroxide ions. The quantitative removal of the DNP groups allows an integrated scheme to pure glycols from commercially available polyethylene glycol mixtures, by bis(2,4-dinitrophenylation), chromatographic separation, end-group removal, using HPLC of the bis-(2,4-dinitrophenyl) glycols for purity monitoring.