A. Sawhney, C. Pathak, J. Hubbell
1993
Citations
22
Influential Citations
869
Citations
Quality indicators
Journal
Macromolecules
Abstract
Macromers having a poly(ethylene glycol) central block, extended with oligomers of α-hydroxy acids such as oligo(dl-lactic acid) or oligo(glycolic acid) and terminated with acrylate groups, were synthesized and characterized with the goal of obtaining a bioerodible hydrogel that could be formed in direct contact with tissues or proteins by photopolymerization of aqueous solutions of the macromer. The amphiphilic nature of the macromers causes them to assume a micellar conformation, which enables them to undergo rapid photopolymerization, resulting in the formation of crosslinked gels