K. Tan, Toshio Matsuda, Y. Takada
1974
Citations
0
Influential Citations
1
Citations
Journal
Journal of Synthetic Organic Chemistry Japan
Abstract
Reduction of 6-cyanohexanoic acid, obtained by the reaction of e-caprolactone with alkali metal cyanide, was studied with cobalt or nickel catalysts. Cobalt catalysts such as Raney Co and Urushibara Co gave 7- aminoheptanoic acid in high yields in dilute ammonia solutions. On the other hand nickel catalysts gave much more iminodiheptanoic acid and much less ω-amino acid. In addition, separation of nickel ion generated in the reaction was more difficult than that of cobalt ion. Some other ω-amino acids were obtained by the above-mentioned operation.