Kim Spielmann, R. D. de Figueiredo, J. Campagne
Apr 18, 2017
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0
Influential Citations
8
Citations
Journal
The Journal of organic chemistry
Abstract
A straightforward strategy for the syntheses of curcumene and ar-himachalene is reported. Synthetic highlights include a catalytic and asymmetric vinylogous Mukaiyama reaction and a stereospecific hydrogenolysis of a tertiary benzylic center using Pd/C or Ni/Raney catalysts. Notably, using Ni/Raney, the stereoselectivity outcome (inversion vs retention) of the hydrogenolysis depends on the tertiary benzylic alcohol substitution.