J. van Loosdregt, R. Spreafico, M. Rossetti
May 1, 2013
Citations
0
Influential Citations
47
Citations
Journal
The Journal of allergy and clinical immunology
Abstract
Although hydroxychloroquine is used for treatment of numerous autoimmune disorders the mechanism is unclear. We here demonstrate that hydroxychloroquine preferentially induces apoptosis of CD45RO+ memory and effector T cells by inhibiting the survival pathway of autophagy.