S. Breiter, D. Schlosser, D. Weiss
Feb 1, 1995
Citations
1
Influential Citations
5
Citations
Journal
Natural Product Letters
Abstract
Abstract The possibility for hydroxylations of androsta-1, 4-diene-3, 17-dione (ADD, II) was studied using different strains of the fungi Penicillium raistrickii, Aspergillus ochraceus, Curvularia lunata and Beauveria bassiana. The isolated products were 15α-hydroxy-ADD (III, P. raistrickii), 11α-hydroxy-ADD (IV, A. ochraceus, B. bassiana), 14-hydroxy-ADD (V, C. lunata) and 7α, 11α-dihydroxy-ADD (VI, B. bassiana). Yields were observed up to 70%. The structures were elucidated by 1H-NMR, 13C-NMR, 2d-NMR, MS and UV/VIS.