E. Chan
2023
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Influential Citations
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Quality indicators
Journal
Journal of Applied Pharmaceutical Science
Abstract
of 3’-hydroxypterostilbene (HPS) and pinostilbene (PS) are reviewed for the first time. Their chemical structures consist of a catechol moiety with two aromatic rings A and B. HPS has two hydroxyl groups and two methoxy groups, while PS has two hydroxyl groups and one methoxy group. Both methoxylated stilbenes are commercially available. The anticancer properties of HPS have been reported in leukemia, colon, and skin cancer cells, while those of PS have been reported in colon, tongue, and nasopharyngeal cancer cells. Other pharmacological properties of HPS include anti-inflammatory, antioxidant, hepatoprotective, anticolitis, antiadipogenesis, sirtuin 1 modulatory, and α-glucosidase inhibitory activities. Those of PS include anti-inflammatory, cytochrome P450 inhibitory, neuroprotective, antioxidant, antityrosinase, α-glucosidase inhibitory, antiplasmodial, lactase dehydrogenase activity release, antimelanogenesis, antiadipogenesis, suppression of hepatic stellate cell activation, and tight junction protection activities. Some fields for further research are suggested. Sources of information in this review were Google, Google Scholar, ScienceDirect, PubMed, J-Stage, and PubChem.