A. Mariappan, K. Rajaguru, Noufal Merukan Chola
Jul 19, 2016
Citations
0
Influential Citations
39
Citations
Journal
The Journal of organic chemistry
Abstract
An efficient synthesis of 3-substituted-5-arylamino-1,2,4-thiadiazoles through intramolecular oxidative S-N bond formation of imidoyl thioureas by phenyliodine(III) bis(trifluoroacetate) is reported. The protocol features a metal-free approach, broad substrate scope, very short reaction times, good to excellent yields, and simple starting materials.