E. Thomas, Kate Pera Bates, M. Jefferson
Sep 1, 1980
Citations
1
Influential Citations
67
Citations
Quality indicators
Journal
Journal of Dental Research
Abstract
The median concentration of hypothiocyanite (OSCN-) in freshly collected whole saliva was 10 μM. The OSCN- concentration increased to a median value of 36 μM during incubation for one h at 37° in vitro. This increase was partially inhibited by adding certain sugars (especially sucrose). The results suggest that OSCN- is a naturally occurring component of human saliva. Also, dietary carbohydrate may inhibit OSCN- accumulation and antimicrobial action in saliva.