Bing Wu, Jianfang Feng, Li-ming Yu
Sep 21, 2018
Citations
2
Influential Citations
62
Citations
Quality indicators
Journal
British Journal of Pharmacology
Abstract
Icariin, a major active ingredient in traditional Chinese medicines, is attracting increasing attention because of its unique pharmacological effects against ischaemic heart disease. The histone deacetylase, sirtuin‐1, plays a protective role in ischaemia/reperfusion (I/R) injury, and this study was designed to investigate the protective role of icariin in models of cardiac I/R injury and to elucidate the potential involvement of sirtuin‐1.