G. Belvedere, C. Pantarotto, V. Rovei
Jun 1, 1976
Citations
0
Influential Citations
14
Citations
Quality indicators
Journal
Journal of pharmaceutical sciences
Abstract
Cyclobenzaprine (40 mg/kg ip) was administered to rats, and six urinary metabolites of this drug were identified. They were the 10, 11-epoxide, the N -oxide, the desmethyl derivative, the hydroxylated and desmethylhydroxylated compounds, and the N-oxide hydroxylated at the 10- or 11-position. Mass spectrometric analysis confirmed their structures.