B. Sleebs, G. Nikolakopoulos, I. Street
Oct 1, 2011
Citations
0
Influential Citations
25
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
4-Aminobenzothieno[3,2-d]pyrimidines were previously identified in a high throughput screening campaign as LIMK1 inhibitors. Scaffold reversal led to the identification of a series of simple 5,6-substituted 4-aminothieno[2,3-d]pyrimidines with low micromolar inhibition of LIMK1.