Tian Li, Jiwen Zhang, Shichuang Ma
Dec 9, 2020
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Influential Citations
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Journal
Pest management science
Abstract
BACKGROUND The Periploca sepium bark root (PSBR) have been regarded as potential botanical insecticides because of its significant insecticidal activity of secondary metabolites. So we isolated several periplocosides from it as promising pesticides to control crop pest in agricultural. RESULTS In our research, two new periplocosides, along with four known periplocosides were isolated from PSBR. The name of new periplocosides were periplocoside T (PST) and periplocoside U (PSU) while another four periplocosides were known as follows: periplocoside A (PSA), periplocoside F (PSF), periplocoside E (PSE) and periplocoside D (PSD). All periplocosides were evalulated its insecticidal activity against 3rd Mythimna separata (Walker) and Plutella xylostella. The biometric data showed that periplocoside T, PSD and PSF had remarkable insecticidal activity against tested insects. And its values of LD50 were 1.31, 3.94 and 3.42 μg·lavare-1 against 3rd M. separata respectively, while the activity of those compounds against 3rd P. xylostella were 5.45, 12.17 and 13.95 μg·lavare-1 respectively. It was apparent that PST, which was further studied the mechanism of action against M. separata, possessed most significant insecticidal activity. The results of enzymatic activity displayed that powerful activation of tryptase, especially weak alkaline tryptase might be dominant factor of causing death of M. separata in vivo. CONCLUSION We herein reported isolation and mechanism of action of insecticidal periplocosides, which established fundament for developping natural agents to prevent damage of crop from pest. This article is protected by copyright. All rights reserved.