H. Guglielmi, A. Jung
1977
Citations
0
Influential Citations
2
Citations
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Journal
Hoppe-Seyler's Zeitschrift fur physiologische Chemie
Abstract
The synthesis and properties of 13 nucleosides derived from 5-aminoimidazole-4-carboxamide and from 4-aminoimidazole-5-carboxamide are described. The isomers were oriented by comparison of their spectra and colour reactions. All compounds were tested for anticancer activity. 4-Amino-1-(alpha-D-arabinopyranosyl)-imidazole-5-carboxamide significantly inhibits the growth of Ehrlich ascites carcinoma (fluid form) in mice.