P. Adler, I. Went, L. Kesztyűs
Sep 1, 1949
Citations
0
Influential Citations
3
Citations
Quality indicators
Journal
Oral surgery, oral medicine, and oral pathology
Abstract
Abstract A brief review is given of the clinical experience in allergy caused by local anesthetics. Synthesis of procaine-azoprotein is described and immunization experiments are reported using this artificial chemospecific antigen. Chemospecificity of the antigen has been proved by precipitation tests. By precipitation inhibition tests it has been shown that there is at least a partial group specificity to local anesthetics (restricted to derivatives of para-aminobenzoic acid), yet not extending over all the derivatives examined.