U. Ahlborg, A. Brouwer, M. Fingerhut
Dec 1, 1992
Citations
7
Influential Citations
205
Citations
Quality indicators
Journal
European journal of pharmacology
Abstract
A scientific evaluation was made of the mechanisms of action of polychlorinated dibenzo-p-dioxins, dibenzofurans and biphenyls. Distinction is made between the aryl-hydrocarbon (Ah) receptor-mediated and non-Ah receptor-mediated toxic responses. Special attention is paid to the applicability of the toxic equivalency factor (TEF) concept.