P. Jacob, Margaret Wilson, N. Benowitz
Jan 2, 1981
Citations
4
Influential Citations
458
Citations
Quality indicators
Journal
Journal of chromatography
Abstract
Improved methods have been developed for the determination of nicotine and its major metabolite, cotinine, in blood, plasma, and urine samples. These methods utilize gas chromatography with alkali flame ionization (nitrogen--phosphorus) detection and structural analogs of nicotine and cotinine as internal standards.