M. Kondo, K. Miyazaki, H. Kodama
Apr 1, 1985
Citations
0
Influential Citations
4
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
A convenient procedure to prepare L-homoglutamic acid (L-2-aminoadipic acid; L-Aad) is described. Chlorination of e-amino group in acetyl-L-lysine ethyl ester with t-butyl hypochlorite (t-BuOCl) followed by dehydrochlorination with pyridine gave ethyl 5-cyanovalerate which on acid hydrolysis afforded L-Aad in good yield.