Yuli Zhang, Chengmiao Xu, Ting Liu
Jun 1, 2018
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Influential Citations
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Journal
Chemistry of Heterocyclic Compounds
Abstract
An improved seven-step synthesis of 4-chloro-7H-pyrrolo[2,3-d]pyrimidine from dimethyl malonate with 31% overall yield is described. The procedure is operationally simple and practical for the synthesis of the 4-chloro-7H-pyrrolo[2,3-d]pyrimidine building block.